Back to Search Start Over

[Antiulcer activity of dibunol in experimental stomach and duodenal ulcers].

Authors :
Shatalov VN
Korman DB
Krutova TV
Sokolov LK
Andrianova OP
Source :
Farmakologiia i toksikologiia [Farmakol Toksikol] 1988 May-Jun; Vol. 51 (3), pp. 60-4.
Publication Year :
1988

Abstract

The antiulcer effect of two medicinal forms (oil solution, liniment) of dibunol in rats with different models of the stomach and duodenum ulcers was studied. The therapeutic activity of dibunol was evaluated by determining the index of ulcer formation as well as during the morphological and histochemical studies. The two medicinal forms of dibunol possessed equal antiulcer activity by all studied criteria. One should note a characteristic property of dibunol--its ability to produce pronounced epithelialization of ulceroerosive and ulceronecrotic lesions of the mucosa without rough scarring.

Details

Language :
Russian
ISSN :
0014-8318
Volume :
51
Issue :
3
Database :
MEDLINE
Journal :
Farmakologiia i toksikologiia
Publication Type :
Academic Journal
Accession number :
3410030