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Multidisciplinary Clinical Considerations in the Treatment of Pediatric Epithelial Ovarian Cancer.
- Source :
-
Journal of pediatric and adolescent gynecology [J Pediatr Adolesc Gynecol] 2021 Dec; Vol. 34 (6), pp. 893-895. Date of Electronic Publication: 2021 May 29. - Publication Year :
- 2021
-
Abstract
- Background: Epithelial ovarian cancers are a rare subset of the less than 1% of ovarian cancers diagnosed in children. This case highlights considerations when caring for these patients.<br />Case: Evaluation of a 12-year-old postmenarchal girl who presented with suprapubic pain revealed a solid/cystic pelvic mass involving bilateral adnexa and elevated Cancer Antigen 125 (CA-125) level. Diagnostic laparoscopy pathology confirmed low-grade papillary serous ovarian carcinoma. Treatment involved surgical tumor debulking, hysterectomy, bilateral salpingo-oophorectomy, and omentectomy; adjuvant chemotherapy with no residual disease, and normalization of Cancer Antigen 125 (CA-125) level; and an aromatase inhibitor for maintenance.<br />Summary and Conclusion: In children with adult-type gynecologic cancers necessitating treatments including surgical sterilization and hormone-modulating therapy, psychological support and developmentally informed collaboration between adult and pediatric services is essential. Clinical decisions for long-term bone and sexual health present opportunities for future research.<br /> (Copyright © 2021. Published by Elsevier Inc.)
Details
- Language :
- English
- ISSN :
- 1873-4332
- Volume :
- 34
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of pediatric and adolescent gynecology
- Publication Type :
- Report
- Accession number :
- 34062234
- Full Text :
- https://doi.org/10.1016/j.jpag.2021.05.009