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Amplification of c-myc and pvt-1 homologous sequences in acute nonlymphatic leukemia.

Authors :
Asker C
Mareni C
Coviello D
Ingvarsson S
Sessarego M
Origone P
Klein G
Sumeigi J
Source :
Leukemia research [Leuk Res] 1988; Vol. 12 (6), pp. 523-7.
Publication Year :
1988

Abstract

Leukemic cells with double minute (DM) chromosomes from an ANLL(M1) patient were found to carry 10-15 fold amplified c-myc sequences. The linked pvt-1-like locus was amplified at the same level, suggesting that the c-myc amplicon is at least 300 kb in size.

Details

Language :
English
ISSN :
0145-2126
Volume :
12
Issue :
6
Database :
MEDLINE
Journal :
Leukemia research
Publication Type :
Academic Journal
Accession number :
3405005
Full Text :
https://doi.org/10.1016/0145-2126(88)90120-8