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Dentipellin, a new antibiotic from culture broth of Dentipellis fragilis.
- Source :
-
The Journal of antibiotics [J Antibiot (Tokyo)] 2021 Aug; Vol. 74 (8), pp. 538-541. Date of Electronic Publication: 2021 May 27. - Publication Year :
- 2021
-
Abstract
- In our effort to find antimicrobial agents from higher fungi, we isolated a new compound, dentipellin (1), along with three known glycosylated diterpenes, erinacines A-C (2-4) from culture broth of Dentipellis fragilis. Their chemical structures were determined by spectroscopic methods including NMR and mass measurements. These compounds exhibited weak antibacterial and antifungal activities.<br /> (© 2021. The Author(s), under exclusive licence to the Japan Antibiotics Research Association.)
- Subjects :
- Anti-Bacterial Agents isolation & purification
Anti-Bacterial Agents pharmacology
Antifungal Agents isolation & purification
Antifungal Agents pharmacology
Bacteria drug effects
Culture Media
Diterpenes isolation & purification
Diterpenes pharmacology
Fungi drug effects
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Molecular Conformation
Anti-Bacterial Agents biosynthesis
Basidiomycota chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1881-1469
- Volume :
- 74
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- The Journal of antibiotics
- Publication Type :
- Academic Journal
- Accession number :
- 34045694
- Full Text :
- https://doi.org/10.1038/s41429-021-00426-1