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Estimating direct and spill-over impacts of political elections on COVID-19 transmission using synthetic control methods.

Authors :
Lim JT
Maung K
Tan ST
Ong SE
Lim JM
Koo JR
Sun H
Park M
Tan KW
Yoong J
Cook AR
Dickens BSL
Source :
PLoS computational biology [PLoS Comput Biol] 2021 May 27; Vol. 17 (5), pp. e1008959. Date of Electronic Publication: 2021 May 27 (Print Publication: 2021).
Publication Year :
2021

Abstract

Mass gathering events have been identified as high-risk environments for community transmission of coronavirus disease 2019 (COVID-19). Empirical estimates of their direct and spill-over effects however remain challenging to identify. In this study, we propose the use of a novel synthetic control framework to obtain causal estimates for direct and spill-over impacts of these events. The Sabah state elections in Malaysia were used as an example for our proposed methodology and we investigate the event's spatial and temporal impacts on COVID-19 transmission. Results indicate an estimated (i) 70.0% of COVID-19 case counts within Sabah post-state election were attributable to the election's direct effect; (ii) 64.4% of COVID-19 cases in the rest of Malaysia post-state election were attributable to the election's spill-over effects. Sensitivity analysis was further conducted by examining epidemiological pre-trends, surveillance efforts, varying synthetic control matching characteristics and spill-over specifications. We demonstrate that our estimates are not due to pre-existing epidemiological trends, surveillance efforts, and/or preventive policies. These estimates highlight the potential of mass gatherings in one region to spill-over into an outbreak of national scale. Relaxations of mass gathering restrictions must therefore be carefully considered, even in the context of low community transmission and enforcement of safe distancing guidelines.<br />Competing Interests: The authors have declared that no competing interests exist.

Details

Language :
English
ISSN :
1553-7358
Volume :
17
Issue :
5
Database :
MEDLINE
Journal :
PLoS computational biology
Publication Type :
Academic Journal
Accession number :
34043622
Full Text :
https://doi.org/10.1371/journal.pcbi.1008959