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Acute myeloid leukemia with T lymphoblastic lymphoma: a case report and literature review.

Authors :
Gao Y
Feng XQ
Liu SS
Xu YJ
Mao CX
Li TL
Hou F
Zhang W
Source :
The Journal of international medical research [J Int Med Res] 2021 May; Vol. 49 (5), pp. 3000605211016138.
Publication Year :
2021

Abstract

Acute myeloid leukemia (AML) with T lymphoblastic lymphoma (T-LBL) is a hematologic tumor of two origins, myeloid and lymphoblastic, and is relatively rare in the same patient. We report a rare case of AML with T-LBL. After the patient was diagnosed, he received standard chemotherapy, which decreased the primitive bone marrow cell percentage from 84% to 5%; however, the enlarged superficial lymph nodes showed no obvious change in size. Immunohistochemistry revealed the following: cluster of differentiation (CD)3 (+), CD5 (+), CD7 (+), transmission disequilibrium test (TDT) (+), myeloperoxidase (MPO) (-), and lysozyme (Lys) (-). The lymph node morphology and immunohistochemical results indicated T-LBL. Therefore, the final diagnosis was AML with T-LBL, with both diseases occurring independently and concurrently.

Details

Language :
English
ISSN :
1473-2300
Volume :
49
Issue :
5
Database :
MEDLINE
Journal :
The Journal of international medical research
Publication Type :
Academic Journal
Accession number :
34038217
Full Text :
https://doi.org/10.1177/03000605211016138