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68Ga-FAPI PET/CT Versus 18F-FDG PET/CT for Detecting Metastatic Lesions in a Case of Radioiodine-Refractory Differentiated Thyroid Cancer.
- Source :
-
Clinical nuclear medicine [Clin Nucl Med] 2021 Nov 01; Vol. 46 (11), pp. 940-942. - Publication Year :
- 2021
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Abstract
- Abstract: 18F-FDG PET/CT is a useful imaging modality for detecting disease recurrence and metastases in patients with radioiodine-refractory differentiated thyroid cancer (RAIR-DTC). However, the sensitivity of 18F-FDG PET/CT in RAIR-DTC is not very satisfactory. 68Ga-FAPI is a promising PET tracer that allowed imaging of various types of cancer. In this case, 68Ga-FAPI showed a far better signal-to-background ratio than 18F-FDG for detecting the RAIR-DTC metastatic lesions, especially for detecting the small pulmonary metastases. Therefore, 68Ga-FAPI may be a promising alternative to 18F-FDG for detecting tumor recurrence and metastases in RAIR-DTC. It could also be used for guiding FAP-targeted radionuclide therapy.<br />Competing Interests: Conflicts of interest and sources of funding: This report was sponsored by the medical and health guidance projects of Xiamen (3502Z20209269 and 3502Z20189010). None of the authors have any conflict of interest to declare.<br /> (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1536-0229
- Volume :
- 46
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Clinical nuclear medicine
- Publication Type :
- Academic Journal
- Accession number :
- 34034326
- Full Text :
- https://doi.org/10.1097/RLU.0000000000003730