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Fungal Infection in Lung Transplantation.
- Source :
-
Seminars in respiratory and critical care medicine [Semin Respir Crit Care Med] 2021 Jun; Vol. 42 (3), pp. 471-482. Date of Electronic Publication: 2021 May 24. - Publication Year :
- 2021
-
Abstract
- Invasive fungal infections threaten lung transplant outcomes with high associated morbidity and mortality. Pharmacologic prophylaxis may be key to prevent posttransplant invasive fungal infections, but cost, adverse effects, and absorption issues are barriers to effective prophylaxis. Trends in fungal infection diagnostic strategies utilize molecular diagnostic methodologies to complement traditional histopathology and culture techniques. While lung transplant recipients are susceptible to a variety of fungal pathogens, Candida spp. and Aspergillus spp. infections remain the most common. With emerging resistant organisms and multiple novel antifungal agents in the research pipeline, it is likely that treatment strategies will continue to evolve.<br />Competing Interests: None declared.<br /> (Thieme. All rights reserved.)
- Subjects :
- Antifungal Agents therapeutic use
Humans
Aspergillosis diagnosis
Aspergillosis drug therapy
Aspergillosis epidemiology
Invasive Fungal Infections diagnosis
Invasive Fungal Infections drug therapy
Invasive Fungal Infections prevention & control
Lung Transplantation adverse effects
Mycoses diagnosis
Mycoses drug therapy
Mycoses prevention & control
Subjects
Details
- Language :
- English
- ISSN :
- 1098-9048
- Volume :
- 42
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Seminars in respiratory and critical care medicine
- Publication Type :
- Academic Journal
- Accession number :
- 34030208
- Full Text :
- https://doi.org/10.1055/s-0041-1729173