Back to Search
Start Over
Iridium-catalyzed stereoselective [3+2] annulation of α-oxocarboxylic acids with 1,3-dienes.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2021 Jun 15; Vol. 57 (48), pp. 5917-5920. - Publication Year :
- 2021
-
Abstract
- The stereoselective annulation of α-oxocarboxylic acids with 1,3-dienes proceeded in the presence of a hydroxoiridium catalyst to give α-hydroxy-γ-lactones in good yields with high 3,5-trans relative stereochemistry. The use of a chiral diene ligand for a cationic iridium complex enabled asymmetric annulation with high enantioselectivity.
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 57
- Issue :
- 48
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 34008643
- Full Text :
- https://doi.org/10.1039/d1cc02003j