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Three is a crowd: Clinical outcomes of a twice daily versus a thrice daily metronidazole dosing strategy from a multicenter study.
- Source :
-
Anaerobe [Anaerobe] 2021 Oct; Vol. 71, pp. 102378. Date of Electronic Publication: 2021 May 07. - Publication Year :
- 2021
-
Abstract
- This was a multicenter, retrospective study of patients with anaerobic bacteremia comparing metronidazole 500 mg every 8 h versus 500 mg every 12 h. Of 782 patients reviewed, 85 met inclusion criteria. There was no significant difference in mortality, length of stay, or escalation of therapy between dosing strategies.<br />Competing Interests: Declaration of competing interest All authors report no conflicts of interest.<br /> (Copyright © 2021 Elsevier Ltd. All rights reserved.)
- Subjects :
- Aged
Bacteremia mortality
Bacteria, Anaerobic classification
Bacteria, Anaerobic drug effects
Bacteria, Anaerobic genetics
Bacteria, Anaerobic isolation & purification
Drug Administration Schedule
Female
Humans
Length of Stay
Male
Middle Aged
Retrospective Studies
Treatment Outcome
Anti-Bacterial Agents administration & dosage
Bacteremia drug therapy
Metronidazole administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1095-8274
- Volume :
- 71
- Database :
- MEDLINE
- Journal :
- Anaerobe
- Publication Type :
- Academic Journal
- Accession number :
- 33965559
- Full Text :
- https://doi.org/10.1016/j.anaerobe.2021.102378