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ecDNA party bus: Bringing the enhancer to you.
- Source :
-
Molecular cell [Mol Cell] 2021 May 06; Vol. 81 (9), pp. 1866-1867. - Publication Year :
- 2021
-
Abstract
- Recent work from Zhu et al. (2021) reveals that extrachromosomal DNA circles harboring enhancers can serve as mobile regulatory elements that interact with chromosomal oncogenes, stimulating high-level gene activity and contributing to tumor heterogeneity and cancer progression.<br /> (Copyright © 2021 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1097-4164
- Volume :
- 81
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Molecular cell
- Publication Type :
- Academic Journal
- Accession number :
- 33961776
- Full Text :
- https://doi.org/10.1016/j.molcel.2021.04.017