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[The cell technologies in modification of mesh materials used in urology].

Authors :
Maiborodin IV
Yarin GY
Vilgelmi IA
Marchukov SV
V MI
Onoprienko NV
Source :
Urologiia (Moscow, Russia : 1999) [Urologiia] 2021 May (2), pp. 94-99.
Publication Year :
2021

Abstract

Based on the literary analysis, the influence of cellular technologies on the results of implantation of mesh materials was studied. The scientific literature of recent years contains a large amount of data devoted to the study of mesh structures and the possibilities of their modification using multipotent stromal cells (MSC) for implantation into patients for correcting tissue defects and pelvic organ prolapse. However, the ideal implant has not yet been created. Additional studies with a longer follow-up period are needed to determine the most successful and safe methods and materials for the restoration of pathologically altered or lost tissues and the transition to clinical trials. It is also yet to come to an unambiguous understanding of the best sources of MSC, ways for stimulation of proliferation, preservation and delivery of these cells into the necessary tissues of the body, to thoroughly study the causes of inefficiency and the risks of developing various complications, especially in the long term. The progress of urological implantology in modern conditions, of course, will be associated with the introduction of modern materials and technologies, including the using MSC.

Details

Language :
Russian
ISSN :
1728-2985
Issue :
2
Database :
MEDLINE
Journal :
Urologiia (Moscow, Russia : 1999)
Publication Type :
Academic Journal
Accession number :
33960166