BRAF -mutated malignant melanoma with chondrosarcomatous differentiation in inguinal nodal metastasis.

Authors :: Abbati F
Altimari A
Corti B
Dika E
Sperandi F
Melotti B
Source :: Clinical case reports [Clin Case Rep] 2021 Mar 07; Vol. 9 (4), pp. 2200-2204. Date of Electronic Publication: 2021 Mar 07 (Print Publication: 2021).
Publication Year :: 2021
Abstract: We report the case of a young woman who developed metastatic melanoma in the inguinal nodal region, which acquired chondrosarcomatous differentiation and preserved the BRAF mutation found in the primary tumor. The patient was treated with a BRAF/MEK inhibitor combination therapy (dabrafenib/trametinib), which was demonstrated to be effective and well-tolerated.<br />Competing Interests: None declared.<br /> (© 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.)

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