A novel case of ocular cicatricial pemphigoid induced by levamisole-adulterated cocaine.

Authors :: Igwe CN
Robinson F
Jones SM
Source :: European journal of ophthalmology [Eur J Ophthalmol] 2021 Apr; Vol. 31 (1_suppl), pp. 11-15.
Publication Year :: 2021
Abstract: Aim: To report a case of ocular cicatricial pemphigoid caused by levamisole-adulterated cocaine.<br />Methods: Case report.<br />Results: A 54-year-old woman with multi-systemic levamisole-induced vasculitis which triggered bilateral cicatrizing conjunctivitis refractory to conventional immunosuppressants due to continued cocaine misuse.<br />Conclusion: Levamisole-induced vasculitis is a significant public health issue due to its popularity as an adulterant to cocaine. Our report suggests that levamisole caused vasculitis and ocular cicatricial pemphigoid in this case. Ocular manifestation of this syndrome is rare.

Subjects :: Cicatrix complications
Combined Modality Therapy
Conjunctivitis diagnosis
Conjunctivitis drug therapy
Female
Humans
Immunosuppressive Agents
Middle Aged
Pemphigoid, Benign Mucous Membrane diagnosis
Pemphigoid, Benign Mucous Membrane drug therapy
Adjuvants, Immunologic toxicity
Cocaine adverse effects
Cocaine-Related Disorders complications
Conjunctivitis chemically induced
Drug Contamination
Levamisole toxicity
Pemphigoid, Benign Mucous Membrane chemically induced

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