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Rhinocerebral mucormycosis secondary to severe acute pancreatitis and diabetic ketoacidosis: a case report.

Authors :
Wang J
Li Y
Luo S
Zheng H
Source :
Diagnostic pathology [Diagn Pathol] 2021 Apr 21; Vol. 16 (1), pp. 34. Date of Electronic Publication: 2021 Apr 21.
Publication Year :
2021

Abstract

Introduction: Rhinocerebral mucormycosis is a rare and severe form of opportunistic fungal infection that can develop rapidly and cause significant mortality, particularly among diabetic patients suffering from ketoacidosis. Diagnosing rhinocerebral mucormycosis during the early stages of infection is challenging.<br />Case Presentation: We describe a case of rhinocerebral mucormycosis secondary to severe acute pancreatitis in a patient suffering from diabetic ketoacidosis. In this case, the condition was not diagnosed during the optimal treatment window. we therefore provide a thorough overview of related clinical findings and histopathological characteristics, and we discuss potential differential diagnoses.<br />Conclusions: In summary, we described a case of rhinocerebral mucormycosis secondary to severe acute pancreatitis in a patient suffering from diabetic ketoacidosis, with the optimal treatment window for this condition having been missed. This report suggests that a definitive mucormycosis diagnosis can be made based upon tissue biopsy that reveals the presence of characteristic hyphae. Early diagnosis and treatment are essential in order to improve patient prognosis.

Details

Language :
English
ISSN :
1746-1596
Volume :
16
Issue :
1
Database :
MEDLINE
Journal :
Diagnostic pathology
Publication Type :
Academic Journal
Accession number :
33882979
Full Text :
https://doi.org/10.1186/s13000-021-01094-3