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ADAM17 Boosts Cholesterol Efflux and Downstream Effects of High-Density Lipoprotein on Inflammatory Pathways in Macrophages.
- Source :
-
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Jun; Vol. 41 (6), pp. 1854-1873. Date of Electronic Publication: 2021 Apr 22. - Publication Year :
- 2021
-
Abstract
- [Figure: see text].
- Subjects :
- ADAM17 Protein genetics
ATP Binding Cassette Transporter 1 metabolism
Animals
Apolipoprotein A-I genetics
Apolipoprotein A-I metabolism
Cells, Cultured
Chemokine CCL2 genetics
Chemokine CCL2 metabolism
Chemokine CXCL1 genetics
Chemokine CXCL1 metabolism
Cholesterol, HDL metabolism
Female
Inflammation genetics
Interleukin-1beta genetics
Interleukin-1beta metabolism
Male
Mice, Inbred C57BL
Mice, Knockout
Receptors, LDL genetics
Receptors, LDL metabolism
Signal Transduction
Tumor Necrosis Factor-alpha genetics
Tumor Necrosis Factor-alpha metabolism
Mice
ADAM17 Protein metabolism
Cholesterol metabolism
Inflammation enzymology
Inflammation Mediators metabolism
Lipoproteins, HDL metabolism
Macrophages, Peritoneal enzymology
Subjects
Details
- Language :
- English
- ISSN :
- 1524-4636
- Volume :
- 41
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Arteriosclerosis, thrombosis, and vascular biology
- Publication Type :
- Academic Journal
- Accession number :
- 33882688
- Full Text :
- https://doi.org/10.1161/ATVBAHA.121.315145