Back to Search
Start Over
Ultrasound-Enhanced Self-Exciting Photodynamic Therapy Based on Hypocrellin B.
- Source :
-
Chemistry, an Asian journal [Chem Asian J] 2021 May 17; Vol. 16 (10), pp. 1221-1224. Date of Electronic Publication: 2021 Apr 21. - Publication Year :
- 2021
-
Abstract
- Peroxalate CL as an energy source to excite photosensitizers has attracted tremendous attention in photodynamic therapy (PDT). In this work, peroxyoxalate CPPO and hypocrellin B (HB)-based nanoparticles (CBNPs) for ultrasound (US)-enhanced self-exciting PDT were designed and prepared. CBNPs showed an excellent therapeutic effect against cancer cells with the assistance of US. This US-enhanced-chemiluminescence system avoids the dependence on external light and provides an example for inspiring more effective and precise strategies for cancer treatment.<br /> (© 2021 Wiley-VCH GmbH.)
- Subjects :
- Antineoplastic Agents chemical synthesis
Antineoplastic Agents chemistry
Cell Line, Tumor
Cell Proliferation drug effects
Cell Survival drug effects
Drug Screening Assays, Antitumor
Humans
Metal-Organic Frameworks chemical synthesis
Metal-Organic Frameworks chemistry
Models, Molecular
Particle Size
Perylene chemistry
Perylene pharmacology
Photosensitizing Agents chemical synthesis
Photosensitizing Agents chemistry
Quinones chemistry
Antineoplastic Agents pharmacology
Metal-Organic Frameworks pharmacology
Perylene analogs & derivatives
Photochemotherapy
Photosensitizing Agents pharmacology
Quinones pharmacology
Ultrasonic Waves
Subjects
Details
- Language :
- English
- ISSN :
- 1861-471X
- Volume :
- 16
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Chemistry, an Asian journal
- Publication Type :
- Academic Journal
- Accession number :
- 33881805
- Full Text :
- https://doi.org/10.1002/asia.202100205