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Adventures of the undead at kinetochores.

Authors :
Elowe S
Source :
Molecular & cellular oncology [Mol Cell Oncol] 2021 Jan 31; Vol. 8 (2), pp. 1876511. Date of Electronic Publication: 2021 Jan 31 (Print Publication: 2021).
Publication Year :
2021

Abstract

At the metaphase-to-anaphase transition, phosphatase activity feeds back to reverse early mitotic phosphorylation events. Our recent work indicates that the pseudokinase domain of the spindle checkpoint protein BUB1 (Budding Uninhibited by Benzimidazoles 1) mitotic checkpoint serine/threonine kinase B (BUB1B, BUBR1) maintains kinase-phosphatase balance at the outer kinetochore during mitotic exit.<br /> (© 2021 Taylor & Francis Group, LLC.)

Details

Language :
English
ISSN :
2372-3556
Volume :
8
Issue :
2
Database :
MEDLINE
Journal :
Molecular & cellular oncology
Publication Type :
Academic Journal
Accession number :
33860079
Full Text :
https://doi.org/10.1080/23723556.2021.1876511