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The AKT1 proto-oncogene maps to human chromosome 14, band q32.

Authors :
Staal SP
Huebner K
Croce CM
Parsa NZ
Testa JR
Source :
Genomics [Genomics] 1988 Jan; Vol. 2 (1), pp. 96-8.
Publication Year :
1988

Abstract

The human AKT1 gene is the proto-oncogene of the viral oncogene v-akt. The AKT1 gene has been localized to human chromosome 14, band q32, proximal to the heavy-chain immunoglobulin locus (IGHM), by analysis of human-hamster somatic cell hybrids and by in situ hybridization. Chromosome rearrangements of this band which occur in T-lymphoid malignancies and Hodgkin's disease may affect the AKT1 gene.

Details

Language :
English
ISSN :
0888-7543
Volume :
2
Issue :
1
Database :
MEDLINE
Journal :
Genomics
Publication Type :
Academic Journal
Accession number :
3384441
Full Text :
https://doi.org/10.1016/0888-7543(88)90114-0