Pharmacological Management of Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome Syndrome: A Proposal of a Treatment Algorithm.

Authors :: Slouma M
Bettaieb H
Rahmouni S
Litaiem N
Dhahri R
Gharsallah I
Metoui L
Louzir B
Source :: Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases [J Clin Rheumatol] 2022 Mar 01; Vol. 28 (2), pp. e545-e551.
Publication Year :: 2022
Abstract: Abstract: Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare chronic disease with marked clinical and radiological heterogeneity. It is characterized by a combination of dermatological and osteoarticular manifestations. The treatment of SAPHO syndrome is not yet codified. It includes several therapeutic options such as anti-inflammatory drugs, bisphosphonates, antibiotics, conventional disease-modifying antirheumatic drugs, and biological treatment.This article aims to provide an updated review of the different pharmacological options for SAPHO syndrome. We also propose a therapeutic algorithm for the management of this disease.<br /> (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)

Subjects :: Algorithms
Humans
Acne Vulgaris diagnosis
Acne Vulgaris drug therapy
Acquired Hyperostosis Syndrome diagnosis
Acquired Hyperostosis Syndrome drug therapy
Hyperostosis diagnosis
Hyperostosis drug therapy
Hyperostosis etiology
Osteitis diagnosis
Osteitis drug therapy
Osteitis etiology
Synovitis

Language :: English
ISSN :: 1536-7355
Volume :: 28
Issue :: 2
Database :: MEDLINE
Journal :: Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
Publication Type :: Academic Journal
Accession number :: 33843770
Full Text :: https://doi.org/10.1097/RHU.0000000000001740

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