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[Troponin T cardiac analysis: clinical cases of the limits of its cardiospecificity].
- Source :
-
Annales de biologie clinique [Ann Biol Clin (Paris)] 2021 Apr 01; Vol. 79 (2), pp. 176-180. - Publication Year :
- 2021
-
Abstract
- Introduction: Myositis are systemic diseases, in which heart damage is possible. Cardiac troponin T is often found to be defective to detect cardiac involvement.<br />Observation: We report cases of two patients with a myositis. Diagnosis was retained based on muscle pain, increase in serum creatinine kinase, and inflammatory muscle damage on MRI. Histology confirmed the diagnosis for one of the two patients. Cardiac troponin T was measured in both patients, to detect myocardial involvement. Despite a serum elevation of this marker, cardiological assessment remained negative (electrocardiogram, cardiac ultrasound, cardiac MRI). Cardiac troponin I was normal in serum because of the absence of correlation with peripheral muscle involvement.<br />Conclusion: Cardiac troponin T is correlated with muscle involvement in patients with myositis. Cardiac troponin I should be preferred because of a better specificity.
- Subjects :
- Biomarkers
Humans
Myocardium
Troponin I
Creatine Kinase
Troponin T
Subjects
Details
- Language :
- French
- ISSN :
- 1950-6112
- Volume :
- 79
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Annales de biologie clinique
- Publication Type :
- Academic Journal
- Accession number :
- 33840644
- Full Text :
- https://doi.org/10.1684/abc.2021.1637