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[Troponin T cardiac analysis: clinical cases of the limits of its cardiospecificity].

Authors :
Coirier V
Pelletier R
Sébillot M
Lefèvre CR
Peltier L
Collet N
Bendavid C
Jégo P
Moreau C
Source :
Annales de biologie clinique [Ann Biol Clin (Paris)] 2021 Apr 01; Vol. 79 (2), pp. 176-180.
Publication Year :
2021

Abstract

Introduction: Myositis are systemic diseases, in which heart damage is possible. Cardiac troponin T is often found to be defective to detect cardiac involvement.<br />Observation: We report cases of two patients with a myositis. Diagnosis was retained based on muscle pain, increase in serum creatinine kinase, and inflammatory muscle damage on MRI. Histology confirmed the diagnosis for one of the two patients. Cardiac troponin T was measured in both patients, to detect myocardial involvement. Despite a serum elevation of this marker, cardiological assessment remained negative (electrocardiogram, cardiac ultrasound, cardiac MRI). Cardiac troponin I was normal in serum because of the absence of correlation with peripheral muscle involvement.<br />Conclusion: Cardiac troponin T is correlated with muscle involvement in patients with myositis. Cardiac troponin I should be preferred because of a better specificity.

Details

Language :
French
ISSN :
1950-6112
Volume :
79
Issue :
2
Database :
MEDLINE
Journal :
Annales de biologie clinique
Publication Type :
Academic Journal
Accession number :
33840644
Full Text :
https://doi.org/10.1684/abc.2021.1637