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Asymmetric dimethylarginine in psychiatric disorders.

Authors :
Braun D
Schlossmann J
Haen E
Source :
Psychiatry research [Psychiatry Res] 2021 Jun; Vol. 300, pp. 113901. Date of Electronic Publication: 2021 Mar 23.
Publication Year :
2021

Abstract

Serum concentrations of asymmetric dimethylarginine (ADMA) in patients with schizophrenia, schizoaffective disorder, bipolar disorder, and depression were determined and compared to serum concentrations in healthy individuals. In all psychiatric diseases investigated, the ADMA concentration was elevated compared to the control group. Patients with recurrent depressive disorder had higher ADMA levels than patients with only one depressive episode. No differences between women and men were found. The elevated ADMA levels suggest that ADMA is involved in the pathophysiology of psychiatric diseases.<br /> (Copyright © 2021 Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
1872-7123
Volume :
300
Database :
MEDLINE
Journal :
Psychiatry research
Publication Type :
Academic Journal
Accession number :
33819866
Full Text :
https://doi.org/10.1016/j.psychres.2021.113901