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Nonsurgical Treatment for Symptomatic Carpal Tunnel Syndrome: A Randomized Clinical Trial Comparing Local Corticosteroid Injection Versus Night Orthosis.

Authors :
de Moraes VY
Queiroz J Jr
Raduan-Neto J
Fernandes M
Okamura A
Belloti JC
Source :
The Journal of hand surgery [J Hand Surg Am] 2021 Apr; Vol. 46 (4), pp. 295-300.e1.
Publication Year :
2021

Abstract

Purpose: For carpal tunnel syndrome (CTS), local corticosteroid injection (corticosteroid), and/or wrist immobilization with night orthosis (orthosis) are commonly prescribed and are supported by strong evidence. The aim of this study was to compare orthosis versus corticosteroid for patients with CTS.<br />Methods: A CTS diagnosis was made clinically and supported by electrodiagnostic study. Patients were randomly allocated to either orthosis or corticosteroid. Clinical assessments were performed before the intervention, within the first week of the intervention, and 1, 3, and 6 months after the intervention. Primary outcomes were improvement in nocturnal paresthesia and Boston-Levine questionnaire (BLQ) score. Secondary outcomes were pain assessed by visual analog scale and complications.<br />Results: Of 100 patients enrolled in the study, 95 completed the planned follow-up (45 in the orthosis arm and 50 in the corticosteroid arm). Corticosteroid injections were superior to orthosis in remission of nocturnal paresthesia (remission rates at 1 month, 84.6% versus 43.83%; 3 months, 71.1% versus 40.4%; and 6 months, 80.3% versus 28.8%). The BLQ scores (functional and symptom subscales) were also more favorable for corticosteroid at 1, 3, and 6 months (minimal clinically important differences for Function > 0.5 and Symptom > 0.16). Pain scores were lower and favored the corticosteroid group. There were no complications in either group.<br />Conclusions: Both options are effective in the short term. Corticosteroid is superior to orthosis for improving CTS-related nocturnal paresthesia, BLQ scores, and pain.<br />Type of Study/level of Evidence: Therapeutic I.<br /> (Copyright © 2021 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1531-6564
Volume :
46
Issue :
4
Database :
MEDLINE
Journal :
The Journal of hand surgery
Publication Type :
Academic Journal
Accession number :
33814051
Full Text :
https://doi.org/10.1016/j.jhsa.2020.11.014