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Isomers of 10-hydroxynortriptyline in geriatric depression.
- Source :
-
Therapeutic drug monitoring [Ther Drug Monit] 1988; Vol. 10 (2), pp. 164-7. - Publication Year :
- 1988
-
Abstract
- In geriatric, depressed inpatients treated with nortriptyline (NT), total unconjugated plasma concentrations of the Z isomer of the 10-hydroxylated metabolite (10-OH-NT) were determined simultaneously with concentrations of the E isomer by high-performance liquid chromatography. Z-10-OH-NT concentrations averaged 14% of E-10-OH-NT concentrations.
Details
- Language :
- English
- ISSN :
- 0163-4356
- Volume :
- 10
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Therapeutic drug monitoring
- Publication Type :
- Academic Journal
- Accession number :
- 3381232
- Full Text :
- https://doi.org/10.1097/00007691-198802000-00008