Back to Search
Start Over
The development of isomer-specific analysis of branched 4-nonylphenol in food for dietary exposure - a critical review of analytical methods and occurrence in foodstuffs.
- Source :
-
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment [Food Addit Contam Part A Chem Anal Control Expo Risk Assess] 2021 May; Vol. 38 (5), pp. 842-855. Date of Electronic Publication: 2021 Mar 30. - Publication Year :
- 2021
-
Abstract
- 4-Nonylphenol (4-NP) is a para-substituted phenolic compound comprising a straight or branched carbon chain group while branched 4-NP consists of 211 possible structural isomers. NP is recognised as an environmental pollutant and exists ubiquitously in both the environment and in food. 4-NP, especially branched 4-NP, has been shown to have the potential role of endocrine disruptor and xeno-oestrogen. Moreover, different NP isomers also exhibit different oestrogen-like activities. Recently, it was reported that the isomer-specific profile of 4-NP in foodstuffs varies greatly between and within food groups. Hence, risk assessment based on total branched 4-NP cannot reflect dietary risk. This study reviews the analytical methods applicable to conduct an isomer-specific analysis of 4-NP and its occurrence in foodstuffs. Lastly, research gaps are identified for future research.
Details
- Language :
- English
- ISSN :
- 1944-0057
- Volume :
- 38
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment
- Publication Type :
- Academic Journal
- Accession number :
- 33784230
- Full Text :
- https://doi.org/10.1080/19440049.2021.1889044