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Au/Ag composite-based SERS nanoprobe of Cr 3 .
- Source :
-
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2021 May; Vol. 413 (11), pp. 2951-2960. Date of Electronic Publication: 2021 Mar 25. - Publication Year :
- 2021
-
Abstract
- Quantitative characterization of Cr <superscript>3+</superscript> , an important element revealing human metabolism and biological environmental variation, is still difficult to achieve by conventional biochemical methods due to the lack of high-sensitivity, real-time techniques with rapid response detection. Using surface-enhanced Raman scattering (SERS), we construct an Au/Ag composite-based SERS nanoprobe for the quantitative characterization of Cr <superscript>3+</superscript> content in solution, in which DL-mercaptosuccinic acid (DL-MSA) is employed for Raman signal enhancement, and 4-mercaptobenzoic acid (4-MBA) is chosen as the Raman reporter. The achieved result demonstrates obvious advantages of the synthesized Au/Ag composite-based SERS nanoprobe in sensitivity and response speed. Importantly, this Au/Ag composite-based SERS nanoprobe might provide a new strategy for dynamic monitoring of Cr <superscript>3+</superscript> content in human metabolism.
Details
- Language :
- English
- ISSN :
- 1618-2650
- Volume :
- 413
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Analytical and bioanalytical chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 33765221
- Full Text :
- https://doi.org/10.1007/s00216-021-03228-4