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ANGPTL3 Inhibition With Evinacumab Results in Faster Clearance of IDL and LDL apoB in Patients With Homozygous Familial Hypercholesterolemia-Brief Report.
- Source :
-
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 May 05; Vol. 41 (5), pp. 1753-1759. Date of Electronic Publication: 2021 Mar 11. - Publication Year :
- 2021
-
Abstract
- [Figure: see text].
- Subjects :
- Adult
Angiopoietin-Like Protein 3
Angiopoietin-like Proteins metabolism
Antibodies, Monoclonal adverse effects
Anticholesteremic Agents adverse effects
Biomarkers blood
Female
Genetic Predisposition to Disease
Homozygote
Humans
Hyperlipoproteinemia Type II blood
Hyperlipoproteinemia Type II diagnosis
Hyperlipoproteinemia Type II genetics
Liver metabolism
Male
Mutation
Netherlands
Pennsylvania
Phenotype
Receptors, LDL genetics
Receptors, LDL metabolism
Time Factors
Treatment Outcome
Angiopoietin-like Proteins antagonists & inhibitors
Antibodies, Monoclonal therapeutic use
Anticholesteremic Agents therapeutic use
Apolipoprotein B-100 blood
Cholesterol, LDL blood
Hyperlipoproteinemia Type II drug therapy
Lipoproteins, IDL blood
Lipoproteins, LDL blood
Liver drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 1524-4636
- Volume :
- 41
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Arteriosclerosis, thrombosis, and vascular biology
- Publication Type :
- Academic Journal
- Accession number :
- 33691480
- Full Text :
- https://doi.org/10.1161/ATVBAHA.120.315204