Dexmedetomidine Induced Polyuria in the Intensive Care Unit.

Authors :: Uddin MM
Sebastian J
Usama M
Raziq FI
Saydain G
Rossi NF
Source :: Case reports in critical care [Case Rep Crit Care] 2021 Feb 20; Vol. 2021, pp. 8850116. Date of Electronic Publication: 2021 Feb 20 (Print Publication: 2021).
Publication Year :: 2021
Abstract: Dexmedetomidine is an α 2-adrenergic used as an adjunct therapy for sedation in the intensive care unit. While it is known to cause polyuria exclusively in perioperative conditions, not many cases are known in the intensive care unit, thus making the diagnosis challenging. We present the case of a 61-year-old male who had developed polyuria secondary to central diabetes insipidus after receiving dexmedetomidine intravenous infusion in the medical ICU. Increased awareness of this uncommon side effect of dexmedetomidine will help clinicians recognize and address it early.<br />Competing Interests: There are no conflicts of interest.<br /> (Copyright © 2021 Mohammed M. Uddin et al.)