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Globetrotting strangles: the unbridled national and international transmission of Streptococcus equi between horses.
- Source :
-
Microbial genomics [Microb Genom] 2021 Mar; Vol. 7 (3). Date of Electronic Publication: 2021 Mar 08. - Publication Year :
- 2021
-
Abstract
- The equine disease strangles, which is characterized by the formation of abscesses in the lymph nodes of the head and neck, is one of the most frequently diagnosed infectious diseases of horses around the world. The causal agent, Streptococcus equi subspecies equi , establishes a persistent infection in approximately 10 % of animals that recover from the acute disease. Such 'carrier' animals appear healthy and are rarely identified during routine veterinary examinations pre-purchase or transit, but can transmit S. equi to naïve animals initiating new episodes of disease. Here, we report the analysis and visualization of phylogenomic and epidemiological data for 670 isolates of S. equi recovered from 19 different countries using a new core-genome multilocus sequence typing (cgMLST) web bioresource. Genetic relationships among all 670 S. equi isolates were determined at high resolution, revealing national and international transmission events that drive this endemic disease in horse populations throughout the world. Our data argue for the recognition of the international importance of strangles by the Office International des Épizooties to highlight the health, welfare and economic cost of this disease. The Pathogenwatch cgMLST web bioresource described herein is available for tailored genomic analysis of populations of S. equi and its close relative S. equi subspecies zooepidemicus that are recovered from horses and other animals, including humans, throughout the world. This article contains data hosted by Microreact.
- Subjects :
- Animals
Female
Genome, Bacterial
Horses
Male
Phylogeny
Streptococcal Infections microbiology
Streptococcal Infections transmission
Streptococcus equi classification
Streptococcus equi genetics
Streptococcus equi physiology
Horse Diseases microbiology
Horse Diseases transmission
Streptococcal Infections veterinary
Streptococcus equi isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 2057-5858
- Volume :
- 7
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Microbial genomics
- Publication Type :
- Academic Journal
- Accession number :
- 33684029
- Full Text :
- https://doi.org/10.1099/mgen.0.000528