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The case of a liver-transplant recipient with severe acute respiratory syndrome coronavirus 2 infection who had a favorable outcome.
- Source :
-
Clinical journal of gastroenterology [Clin J Gastroenterol] 2021 Jun; Vol. 14 (3), pp. 842-845. Date of Electronic Publication: 2021 Mar 06. - Publication Year :
- 2021
-
Abstract
- The outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in 2019; thereafter, the COVID-19 outbreak became a health emergency of international concern. The impact of COVID-19 on liver-transplant recipients is unclear. Thus, it is currently unknown whether liver-transplant recipients are at a higher risk of developing complications related to COVID-19. Here, we report the case of liver-transplant recipients who were infected with SARS-CoV-2. A 20-year-old man who had undergone living-donor liver transplantation from his father at 5 years of age because of congenital biliary atresia was referred to our hospital for SARS-CoV-2 infection. Chest computed tomography did not show any abnormalities; however, laboratory results revealed liver dysfunction. He received tacrolimus as maintenance therapy that was continued at the same dose. He has not developed severe pulmonary disease and was discharged after 10 days of hospitalization. Limited data are available on post-transplant patients with COVID-19, and this case of a young patient without metabolic comorbidities did not show any association of severe COVID-19 under tacrolimus treatment. The progression of COVID-19 in liver-transplant recipients is complex, and COVID-19 risk should be evaluated in each patient until the establishment of optimal guidelines.
- Subjects :
- Adult
COVID-19 Testing
Humans
Immunocompromised Host
Living Donors
Male
Postoperative Complications diagnosis
Postoperative Complications etiology
SARS-CoV-2 immunology
Transplant Recipients
Treatment Outcome
Young Adult
COVID-19 diagnosis
Immunosuppressive Agents therapeutic use
Liver Transplantation adverse effects
Postoperative Complications drug therapy
SARS-CoV-2 isolation & purification
Tacrolimus therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1865-7265
- Volume :
- 14
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Clinical journal of gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 33675512
- Full Text :
- https://doi.org/10.1007/s12328-021-01374-x