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[Diagnostic and therapeutic management of operable bronchopulmonary carcinoid tumours].

Authors :
Snene H
Badri I
Mehiri N
Ben Salah N
Blibech H
Aouina H
Belhadj S
Boussen H
Chaouch N
Charfi R
Fenniche S
Gharbi L
Ghrairi H
Hamzaoui A
Megdiche L
Merai S
Mezni F
Tritar F
Daghfous J
Marghli A
Louzir B
Source :
Revue des maladies respiratoires [Rev Mal Respir] 2021 Mar; Vol. 38 (3), pp. 249-256. Date of Electronic Publication: 2021 Mar 02.
Publication Year :
2021

Abstract

Introduction: Bronchial carcinoid tumours (CT), divided into typical carcinoid (TC) or atypical carcinoid (AC), are rare tumours whose therapeutic management remains unspecified.<br />Methods: Retrospective study collecting cases of bronchial CT operated at the thoracic surgery department of Abderrahmane-Mami hospital of Ariana and recruited from the pneumology departments of Northern Tunisia, during a 12-year period.<br />Results: Ninety patients were collected (74 cases of TC and 16 cases of AC). The mean age was 45 years and the sex ratio H/F=0.5. The chest X-ray was normal in 11 cases, as well as flexible bronchoscopy in seven cases. The tumour was classified: stage IA (10 cases), IIA (28 cases), IIB (31 cases), IIIA (15 cases) and IIIB (six cases). Surgery resulted in a complete resection in 78 patients, an extensive resection in six patients, and a conservative resection in six patients. Adjuvant chemotherapy was given in 10 patients. The survival was 84% at five years and 42% at 10 years.<br />Conclusion: The prognosis of CT depends directly on the histological subtype. It is excellent for TC after complete resection, unlike ACs that are similar to well-differentiated bronchial carcinomas.<br /> (Copyright © 2021 SPLF. Published by Elsevier Masson SAS. All rights reserved.)

Details

Language :
French
ISSN :
1776-2588
Volume :
38
Issue :
3
Database :
MEDLINE
Journal :
Revue des maladies respiratoires
Publication Type :
Academic Journal
Accession number :
33674138
Full Text :
https://doi.org/10.1016/j.rmr.2021.02.062