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[Progress of studies on anti-breast tumor mechanism of alkaloids].

Authors :
Zhang P
Zhang YF
Chen QL
DU WC
Yao H
Zhao M
Source :
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2021 Jan; Vol. 46 (2), pp. 312-319.
Publication Year :
2021

Abstract

Breast tumor has become one of the malignant tumors with the highest incidence, and is a serious threat to human health, especially to women. Chemotherapy is an important anti-breast tumor therapy, which can be used in almost every stage of breast tumor therapy alone or in the combination with surgery and radiation therapy. Alkaloids are a kind of ubiquitous natural products, and important active components of various medicinal plants. A large number of studies have shown that alkaloids could exert an anti-breast tumor effect by inhibiting proliferation, metastasis and angiogenesis, resisting mitosis, promoting apoptosis and autophagy, and triggering cell cycle arrest. The extensive anti-breast tumor effect makes alkaloids an important candidate drug source. This paper reviews the anti-breast tumor mechanism of natural products of alkaloids.

Details

Language :
Chinese
ISSN :
1001-5302
Volume :
46
Issue :
2
Database :
MEDLINE
Journal :
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Publication Type :
Academic Journal
Accession number :
33645117
Full Text :
https://doi.org/10.19540/j.cnki.cjcmm.20201015.601