Acute kidney injury pathology and pathophysiology: a retrospective review.

Authors :: Gaut JP
Liapis H
Source :: Clinical kidney journal [Clin Kidney J] 2020 Oct 10; Vol. 14 (2), pp. 526-536. Date of Electronic Publication: 2020 Oct 10 (Print Publication: 2021).
Publication Year :: 2020
Abstract: Acute kidney injury (AKI) is the clinical term used for decline or loss of renal function. It is associated with chronic kidney disease (CKD) and high morbidity and mortality. However, not all causes of AKI lead to severe consequences and some are reversible. The underlying pathology can be a guide for treatment and assessment of prognosis. The Kidney Disease: Improving Global Outcomes guidelines recommend that the cause of AKI should be identified if possible. Renal biopsy can distinguish specific AKI entities and assist in patient management. This review aims to show the pathology of AKI, including glomerular and tubular diseases.<br /> (© The Author(s) 2020. Published by Oxford University Press on behalf of ERA-EDTA.)