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SARS-CoV-2 Infection Hospitalization Rate and Infection Fatality Rate Among the Non-Congregate Population in Connecticut.
- Source :
-
The American journal of medicine [Am J Med] 2021 Jun; Vol. 134 (6), pp. 812-816.e2. Date of Electronic Publication: 2021 Feb 20. - Publication Year :
- 2021
-
Abstract
- Background: Infection fatality rate and infection hospitalization rate, defined as the proportion of deaths and hospitalizations, respectively, of the total infected individuals, can estimate the actual toll of coronavirus disease 2019 (COVID-19) on a community, as the denominator is ideally based on a representative sample of a population, which captures the full spectrum of illness, including asymptomatic and untested individuals.<br />Objective: To determine the COVID-19 infection hospitalization rate and infection fatality rate among the non-congregate population in Connecticut between March 1 and June 1, 2020.<br />Methods: The infection hospitalization rate and infection fatality rate were calculated for adults residing in non-congregate settings in Connecticut prior to June 2020. Individuals with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies were estimated using the seroprevalence estimates from the recently conducted Post-Infection Prevalence study. Information on total hospitalizations and deaths was obtained from the Connecticut Hospital Association and the Connecticut Department of Public Health, respectively.<br />Results: Prior to June 1, 2020, nearly 113,515 (90% confidence interval [CI] 56,758-170,273) individuals were estimated to have SARS-CoV-2 antibodies, and there were 7792 hospitalizations and 1079 deaths among the non-congregate population. The overall COVID-19 infection hospitalization rate and infection fatality rate were estimated to be 6.86% (90% CI, 4.58%-13.72%) and 0.95% (90% CI, 0.63%-1.90%), respectively, and there was variation in these rate estimates across subgroups; older people, men, non-Hispanic Black people, and those belonging to 2 of the counties had a higher burden of adverse outcomes, although the differences between most subgroups were not statistically significant.<br />Conclusions: Using representative seroprevalence estimates, the overall COVID-19 infection hospitalization rate and infection fatality rate were estimated to be 6.86% and 0.95%, respectively, among community residents in Connecticut.<br /> (Published by Elsevier Inc.)
- Subjects :
- COVID-19 Serological Testing methods
COVID-19 Serological Testing statistics & numerical data
Carrier State epidemiology
Connecticut epidemiology
Female
Humans
Male
Middle Aged
Mortality
Outcome Assessment, Health Care
Risk Assessment methods
Risk Assessment statistics & numerical data
Seroepidemiologic Studies
COVID-19 epidemiology
COVID-19 immunology
COVID-19 prevention & control
COVID-19 virology
Communicable Disease Control organization & administration
Communicable Disease Control statistics & numerical data
Disease Transmission, Infectious prevention & control
Disease Transmission, Infectious statistics & numerical data
Hospitalization statistics & numerical data
SARS-CoV-2 isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 1555-7162
- Volume :
- 134
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- The American journal of medicine
- Publication Type :
- Academic Journal
- Accession number :
- 33617808
- Full Text :
- https://doi.org/10.1016/j.amjmed.2021.01.020