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Case Report: Successful Management of Conidiobolus Lamprauges Rhinitis in a Dog.

Authors :
Jaffey JA
Hostnik ET
Hoffman AR
Jay M
Ferguson SH
Wiederhold NP
Source :
Frontiers in veterinary science [Front Vet Sci] 2021 Feb 05; Vol. 8, pp. 633695. Date of Electronic Publication: 2021 Feb 05 (Print Publication: 2021).
Publication Year :
2021

Abstract

This is a case of Conidiobolus lamprauges rhinitis in a Goldendoodle, that was presented for evaluation of sneezing, coughing, lethargy, as well as right-sided epistaxis and clear ocular discharge. Computed tomography revealed a large amount of soft tissue within the right nasal passage that obscured the osseous turbinates from the right maxillary canine tooth to the right side of the choanae. Biopsies revealed eosinophilic granulomas with variable number of basophilic to negatively staining, septate, fungal hyphae with non-parallel walls and irregular branching that were subsequently determined to be Conidiobolus lamprauges via panfungal PCR and sequencing. Complete and sustained resolution of clinical disease was achieved after 75 days of systemic antifungal therapy. This report describes for the first time, important clinical features of a dog with nasal conidiobolomycosis that will facilitate its recognition, prognostication, and treatment in clinical practice.<br />Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.<br /> (Copyright © 2021 Jaffey, Hostnik, Hoffman, Jay, Ferguson and Wiederhold.)

Details

Language :
English
ISSN :
2297-1769
Volume :
8
Database :
MEDLINE
Journal :
Frontiers in veterinary science
Publication Type :
Report
Accession number :
33614770
Full Text :
https://doi.org/10.3389/fvets.2021.633695