Rationale for the Role of Heparin and Related GAG Antithrombotics in COVID-19 Infection.

Authors :: Magnani HN
Source :: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis [Clin Appl Thromb Hemost] 2021 Jan-Dec; Vol. 27, pp. 1076029620977702.
Publication Year :: 2021
Abstract: The SARS-CoV-2 pandemic has focused attention on prevention, restriction and treatment methods that are acceptable worldwide. This means that they should be simple and inexpensive. This review examines the possible role of glycosaminoglycan (GAG) antithrombotics in the treatment of COVID-19. The pathophysiology of this disease reveals a complex interplay between the hemostatic and immune systems that can be readily disrupted by SARS-CoV-2. Some of the GAG antithrombotics also possess immune-modulatory actions and since they are relatively inexpensive they could play an important role in the management of COVID-19 and its complications.

Language :: English
ISSN :: 1938-2723
Volume :: 27
Database :: MEDLINE
Journal :: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Publication Type :: Academic Journal
Accession number :: 33539214
Full Text :: https://doi.org/10.1177/1076029620977702

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