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Risk factors for suicidal tendency in people with epilepsy in China: a case-control study.
- Source :
-
Scientific reports [Sci Rep] 2021 Feb 02; Vol. 11 (1), pp. 2742. Date of Electronic Publication: 2021 Feb 02. - Publication Year :
- 2021
-
Abstract
- People with epilepsy (PWE) have an increased suicide prevalence. This study aimed to identify the risk factors for suicidal tendency among PWE in West China. A nested case-control study was designed in a cohort of patients with epilepsy (n = 2087). In total, 28 variates were calculated. In the univariate analysis, unemployment, low income, seizure frequency, seizure-free time, infectious or structural etiology, levetiracetam or phenobarbital use, anxiety, depression, and stigma were associated with suicidal tendency. A multivariate analysis indicated that unemployment (odds ratio [OR] 5.74, 95% confidence interval [CI] 2.13-15.48), levetiracetam use (OR 2.80, 95%CI 1.11-7.05), depression (C-NDDI-E score ≥ 13; OR 3.21, 95%CI 1.26-8.21), and stigma (SSCI score ≥ 16; OR 6.67, 95%CI 1.80-24.69) were independently associated with suicidal tendency. Conditional inference tree analysis indicated that SSCI and C-NDDI-E scores could effectively identify patients with suicidal tendency. Thus, this study suggests that unemployment, levetiracetam use, depression, and stigma are independent risk factors for suicidal tendency in PWE in China.
- Subjects :
- Adolescent
Adult
Case-Control Studies
China epidemiology
Depression psychology
Epilepsy diagnosis
Epilepsy drug therapy
Female
Follow-Up Studies
Humans
Income statistics & numerical data
Levetiracetam therapeutic use
Male
Prevalence
Risk Factors
Severity of Illness Index
Unemployment statistics & numerical data
Young Adult
Depression epidemiology
Epilepsy psychology
Social Stigma
Suicidal Ideation
Unemployment psychology
Subjects
Details
- Language :
- English
- ISSN :
- 2045-2322
- Volume :
- 11
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Scientific reports
- Publication Type :
- Academic Journal
- Accession number :
- 33531579
- Full Text :
- https://doi.org/10.1038/s41598-021-81870-9