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Patient Age and Long-term Survival in Colorectal Cancer Patients Who Undergo Emergency Surgery.
- Source :
-
Anticancer research [Anticancer Res] 2021 Feb; Vol. 41 (2), pp. 1069-1076. - Publication Year :
- 2021
-
Abstract
- Background/aim: Emergency surgery for colorectal cancer (CRC) is a high-risk procedure with high morbidity and mortality rates, especially for older patients. The relationship between patient age status and long-term outcomes is unclear. We hypothesize that patient age might be associated with long-term outcomes in patients with CRC who undergo emergency surgery.<br />Patients and Methods: Utilizing a database of CRC patients who received emergency surgery, we examined the prognostic association of patient age.<br />Results: The ≥80-years group was significantly associated with American Society of Anesthesiologists (ASA) physical status, bowel obstruction, N stage, shorter operating time, and less adjuvant chemotherapy (all p<0.03); and also, with shorter recurrence-free survival [multivariable hazard ratio, 2.79; 95% confidence interval, 1.13-7.21; p=0.026]. ASA status and adjuvant chemotherapy were significantly associated with recurrence-free survival (all p<0.03).<br />Conclusion: Advanced age is associated with shorter recurrence-free survival in CRC patients who undergo emergency surgery.<br /> (Copyright © 2021 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.)
- Subjects :
- Age Factors
Aged
Aged, 80 and over
Chemotherapy, Adjuvant
Colorectal Neoplasms drug therapy
Databases, Factual
Emergency Treatment adverse effects
Female
Humans
Intestinal Obstruction epidemiology
Male
Middle Aged
Operative Time
Postoperative Complications epidemiology
Prognosis
Retrospective Studies
Survival Analysis
Colorectal Neoplasms mortality
Colorectal Neoplasms surgery
Emergency Treatment methods
Intestinal Obstruction etiology
Subjects
Details
- Language :
- English
- ISSN :
- 1791-7530
- Volume :
- 41
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Anticancer research
- Publication Type :
- Academic Journal
- Accession number :
- 33517317
- Full Text :
- https://doi.org/10.21873/anticanres.14864