Vulvar epithelioid sarcoma: A case report with literature review.

Objective: To report a case of vulvar epithelioid sarcoma, a rare type of tumor that has been reported in 37 cases in the English literature to date.
Case Report: We report three cases of vulvar epithelioid sarcoma, proximal type. Wide excisions of the mass were performed with margins free of tumor in all three cases.
Conclusion: Due to its low incidence, there are no evidence-based diagnostic algorithms or published recommendations for treatment. Locoregional lymph node involvement, vascular invasion, tumor size larger than 2 cm, deep localization, presence of necrosis, and a high mitotic index are known as poor prognostic factors. Adjuvant radiotherapy is advisable in the presence of a high-grade tumor or positive margins. The beneficial effect of adjuvant chemotherapy is not well established. Treatment decisions should be made based on the individual case presentation and pathology evaluation.
Competing Interests: Declaration of competing interest The authors of this publication disclose that there are no relevant financial, personal, political, intellectual or religious interests to declare. The terms of this arrangement have been reviewed and approved by Samsung Medical Center in accordance with its policy on objectivity in research.
(Copyright © 2021. Published by Elsevier B.V.)