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Armochaetoglasins J and K: new cytochalasans from Chaetomium globosum .

Authors :
Cheng L
Zheng X
Li Q
Wei MS
Chen CM
Zhu HC
Zeng CL
Hao XC
Zhang YH
Source :
Natural product research [Nat Prod Res] 2022 Jul; Vol. 36 (14), pp. 3603-3609. Date of Electronic Publication: 2021 Jan 25.
Publication Year :
2022

Abstract

Two novel cytochalasans, armochaetoglasin J ( 1 ) and armochaetoglasin K ( 2 ), along with 14 known analogues ( 3 - 16 ) were isolated from Chaetomium globosum. Their structures were elucidated by HRESIMS, NMR spectroscopy, single-crystal X-ray crystallography, and ECD spectra. Armochaetoglasins J and K were found to be inactive against the HepG2, HT-29, K562, HL-60, and A549 cancer cell lines.

Details

Language :
English
ISSN :
1478-6427
Volume :
36
Issue :
14
Database :
MEDLINE
Journal :
Natural product research
Publication Type :
Academic Journal
Accession number :
33487054
Full Text :
https://doi.org/10.1080/14786419.2021.1872568