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Economical and easily detectable markers of digestive tumors: platelet parameters.
- Source :
-
Biomarkers in medicine [Biomark Med] 2021 Feb; Vol. 15 (3), pp. 157-166. Date of Electronic Publication: 2021 Jan 21. - Publication Year :
- 2021
-
Abstract
- Aim: This study aimed to evaluate the clinical values of platelet parameters in patients with digestive tumors. Patients & methods: A total of 974 people were classified into three groups: malignant group, patients with digestive malignant tumors; benign group, patients with benign tumors; and normal group: healthy individuals. Results: Compared with the benign and normal groups, the malignant group showed significantly increased platelet count (PLT) and plateletcrit (PCT) and significantly reduced mean platelet volume (MPV) and platelet-large cell rate (P-LCR, p < 0.001). Elevated PLT and PCT and reduced MPV and P-LCR indicated poor overall survival in patients with digestive tumors. Conclusion: PLT, PCT, MPV and P-LCR were proven to be predictive biomarkers for patients with digestive malignant tumors. Elevated PLT and PCT or decreased MPV and P-LCR indicated poor overall survival.
Details
- Language :
- English
- ISSN :
- 1752-0371
- Volume :
- 15
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Biomarkers in medicine
- Publication Type :
- Academic Journal
- Accession number :
- 33474972
- Full Text :
- https://doi.org/10.2217/bmm-2020-0203