Pellagra a review exploring causes and mechanisms, including isoniazid-induced pellagra.

Authors :: Prabhu D
Dawe RS
Mponda K
Source :: Photodermatology, photoimmunology & photomedicine [Photodermatol Photoimmunol Photomed] 2021 Mar; Vol. 37 (2), pp. 99-104. Date of Electronic Publication: 2021 Feb 02.
Publication Year :: 2021
Abstract: Pellagra is a clinical syndrome caused by a deficiency of niacin (nicotinic acid) and/or its precursor tryptophan. The cardinal manifestations are 4 D's: dermatitis, diarrhoea, dementia and in worst case death. Increased use of isoniazid prophylaxis along with antiretroviral therapy in countries where latent tuberculosis is common has been associated with increased presentations with pellagra.<br /> (© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Subjects :: AIDS-Related Opportunistic Infections drug therapy
HIV Infections drug therapy
Humans
Pellagra chemically induced
Antitubercular Agents adverse effects
Isoniazid adverse effects
Pellagra etiology

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