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Sex bias of females in survival from cancer and infections. Is X the answer?

Authors :
Emran AA
Gallagher SJ
Tiffen JC
Hersey P
Source :
British journal of cancer [Br J Cancer] 2021 Mar; Vol. 124 (7), pp. 1184-1186. Date of Electronic Publication: 2021 Jan 19.
Publication Year :
2021

Abstract

Major differences in survival of men and women from infectious diseases and cancers have been highlighted by death rates from COVID-19 infections. In cancer, attention has been focussed on differences in gene expression from X chromosomes in men and women with a preponderance of genes involved in immune responses being expressed in women. Important findings have been that some of the genes are important epigenetic regulators that play fundamental roles in immune responses.

Details

Language :
English
ISSN :
1532-1827
Volume :
124
Issue :
7
Database :
MEDLINE
Journal :
British journal of cancer
Publication Type :
Academic Journal
Accession number :
33469152
Full Text :
https://doi.org/10.1038/s41416-020-01245-1