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Ileal Intussusception in an Adult Caused by a Locally Invasive Inflammatory Fibroid Polyp: A Case Report.
- Source :
-
Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia [Rev Esp Patol] 2021 Jan-Mar; Vol. 54 (1), pp. 65-69. Date of Electronic Publication: 2020 Jul 21. - Publication Year :
- 2021
-
Abstract
- Inflammatory fibroid polyps (IFPs) are rare mesenchymal neoplasms affecting the gastrointestinal tract which are considered benign and noninvasive. We present a case of an invasive IFP in a 46-year-old woman who presented with signs of intestinal obstruction due to ileal intussusception. A segment of the small intestine was resected and subsequently intestinal continuity was restored. A polypoid lesion was found obstructing the lumen. Histopathology revealed a mesenchymal proliferation of spindle and stellate cells, without cytological atypia, arranged in a fibromyxoid stroma. The tumor cells were located in the submucosa but also infiltrated the muscularis propria and the subserosa and were CD34 positive. The molecular study by PCR showed mutation in exon 12 of the PDGFRA gene. IFP is considered a true neoplasm and can also be considered as a potentially invasive lesion.<br /> (Copyright © 2020 Sociedad Española de Anatomía Patológica. Publicado por Elsevier España, S.L.U. All rights reserved.)
- Subjects :
- Exons genetics
Female
Humans
Ileal Diseases diagnostic imaging
Ileal Diseases etiology
Intestinal Polyps complications
Intestinal Polyps diagnostic imaging
Intussusception diagnostic imaging
Intussusception etiology
Middle Aged
Mutation
Receptor, Platelet-Derived Growth Factor alpha genetics
Ileal Diseases pathology
Intestinal Polyps pathology
Intussusception pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1988-561X
- Volume :
- 54
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia
- Publication Type :
- Report
- Accession number :
- 33455696
- Full Text :
- https://doi.org/10.1016/j.patol.2020.06.001