Mortality and glycemic control among patients with acute and chronic myeloid leukemia and diabetes: a case-control study.

Aim: We examined the association between diabetes and survival in patients with acute and chronic myeloid leukemia and the association of leukemia with glycemic control.
Patients & Methods: Patients with leukemia with and without diabetes (2007-2015) were retrospectively identified and matched 1:1 (n = 70 per group). Overall survival was estimated by the Kaplan-Meier method. Hemoglobin A _1c  and glucose levels the year after leukemia diagnosis were compared by mixed models.
Results: Among 25 of 70 patients with diabetes, mean hemoglobin A _1c during the year after leukemia diagnosis was 6.8%. Kaplan-Meier-estimated 3-year survival was 46% for diabetes patients versus 45% for controls (p = 0.79).
Conclusion: No associations were found between leukemia, diabetes, survival and glycemic control.
Competing Interests: Financial & competing interests disclosure The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties. No writing assistance was utilized in the production of this manuscript.
(© 2020 Mayo Foundation for Medical Education and Research.)