Impacts of implementing Healthy Building guidelines for daily PM 2.5 limit on premature deaths and economic losses in urban China: A population-based modeling study.

Given a large fraction of people's exposure to urban PM _2.5 occur indoors, reducing indoor PM _2.5 levels may offer a more feasible and immediate way to save substantial lives and economic losses attributable to PM _2.5 exposure. We aimed to estimate the premature mortality and economic loss reductions associated with achieving the newly established Chinese indoor air guideline and a few hypothetical indoor PM _2.5 guideline values. We used outdoor PM _2.5 concentrations from 1497 monitoring sites in 339 Chinese cities in 2015, coupled with a steady-state mass balance model, to estimate indoor concentrations of outdoor-infiltrated PM _2.5 . Using province-specific time-activity patterns for urban residents, we estimated outdoor and indoor exposures to PM _2.5 of outdoor origin. We then proceeded to use localized census-based concentration-response models and the value of statistical life estimates to calculate premature deaths and economic losses attributable to PM _2.5 exposure across urban China. Finally, we estimated potentially avoidable mortality and corresponding economic losses by meeting the current 24-hour based guideline and various hypothetical indoor limits for PM _2.5 . In 2015 in urban areas of mainland China, the city-specific annual mean outdoor and indoor PM _2.5 concentrations ranged 9-108 μg/m ³ and 5-56 μg/m ³ , respectively. Indoor exposures contributed 62%-91% daily and 68%-83% annually to the total time-weighted exposures. The potential reductions in total deaths and economic losses for the scenario in which daily indoor concentrations met the current guideline of 75 μg/m ³ , 37.5 μg/m ³ , and 25 μg/m ³ were 16.9 (95% CI: 0.7-62.1) thousand, 87.7 (95% CI: 9.7-197.7) thousand, and 165.5 (95% CI: 30.8-304.0) thousand, respectively. The corresponding reductions in economic losses were 5.7 (95% CI: 0.2-34.8) billion, 29.4 (95% CI: 2.4-109.6) billion, and 55.2 (95% CI: 7.7-168.0) billion US Dollars, respectively. Deaths and economic losses would be reduced exponentially within the range of 0-75 μg/m ³ for hypothetical indoor PM _2.5 limits. The findings demonstrate the effectiveness of reducing indoor concentrations of outdoor-originated PM _2.5 in saving substantial lives and economic losses in China. The analysis provides quantitative evidence to support the implementation of an indoor air quality guideline or standard for PM _2.5 .
(Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.)