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Iso-octenidine: Promising Octenidine Analogue with Improved Solubility.

Authors :
Yakuschenko IK
Pozdeeva NN
Mumyatova VA
Terentiev AA
Gadomsky SY
Source :
Current organic synthesis [Curr Org Synth] 2021; Vol. 18 (5), pp. 443-445.
Publication Year :
2021

Abstract

Iso-octenidine, an isomer of octenidine dihydrochloride, was synthesized and studied for the first time. Iso-octenidine was demonstrated to be 3-fold more soluble in water in comparison to original octenidine, and both substances had remarkably similar antibacterial activity (tested on Escherichia Coli and Micrococcus luteus).<br /> (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)

Details

Language :
English
ISSN :
1570-1794
Volume :
18
Issue :
5
Database :
MEDLINE
Journal :
Current organic synthesis
Publication Type :
Academic Journal
Accession number :
33390116
Full Text :
https://doi.org/10.2174/1570179417666201231104453