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Comparative analysis of secondary metabolite gene clusters in different strains of Magnaporthe oryzae.
- Source :
-
FEMS microbiology letters [FEMS Microbiol Lett] 2021 Jan 26; Vol. 368 (1). - Publication Year :
- 2021
-
Abstract
- Rice blast caused by Magnaporthe oryzae continues to be a major constraint in rice production worldwide. Rice is one of the staple crops in India and rice blast causes huge economic losses. Interestingly, the Indian subcontinent is the centre for origin and diversity of rice as well as the Magnaporthe species complex. Secondary metabolites are known to play important role in pathogenesis and M. oryzae has high potential of genes involved in secondary metabolism but, unfortunately most of them remain uncharacterized. In the present study, we analysed the draft genome assemblies of M. oryzae strains isolated from different parts of India, for putative secondary metabolite key gene (SMKG) clusters encoding polyketide synthases, non-ribosomal peptide synthetases, diterpene cyclases and dimethylallyl tryptophan synthase. Based on the complete genome sequence of 70-15 strain and its previous reports of identified SMKGs, we have identified the key genes for the interrogated strains. Expression analysis of these genes amongst different strains indicates how they have evolved depending on the host and environmental conditions. To our knowledge, this study is first of its kind where the secondary metabolism genes and their role in functional adaptation were studied across several strains of M. oryzae.<br /> (© The Author(s) 2020. Published by Oxford University Press on behalf of FEMS.)
- Subjects :
- Alkyl and Aryl Transferases genetics
Alkyl and Aryl Transferases metabolism
Ascomycota classification
Ascomycota enzymology
Fungal Proteins metabolism
Oryza microbiology
Peptide Synthases genetics
Peptide Synthases metabolism
Plant Diseases microbiology
Polyketide Synthases genetics
Polyketide Synthases metabolism
Secondary Metabolism
Ascomycota genetics
Ascomycota metabolism
Fungal Proteins genetics
Multigene Family
Subjects
Details
- Language :
- English
- ISSN :
- 1574-6968
- Volume :
- 368
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- FEMS microbiology letters
- Publication Type :
- Academic Journal
- Accession number :
- 33355334
- Full Text :
- https://doi.org/10.1093/femsle/fnaa216