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First report of a blaNDM-resistant gene in a Klebsiella aerogenes clinical isolate from Brazil.

Authors :
Soares CRP
Oliveira-Júnior JB
Firmo EF
Source :
Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2020 Dec 21; Vol. 54, pp. e02622020. Date of Electronic Publication: 2020 Dec 21 (Print Publication: 2020).
Publication Year :
2020

Abstract

Introduction: Carbapenemase-resistant enterobacteria that produce the bla NDM gene are found worldwide. However, this is the first report of blaNDM in Klebsiella aerogenes in Brazil.<br />Methods: The identification of bacterial species was performed using anautomated system and confirmed by biochemical tests, 16S rRNA gene sequencing, and detection of resistance genes.<br />Results: The clinical isolate showed minimum inhibitory concentration resistance to meropenem and polymyxin B at 8mg/L and 4mg/L, respectively. Only the blaNDM gene was detected.<br />Conclusions: The current report of the blaNDM gene in isolated MDR enterobacteria indicates that this gene can spread silently in a hospital setting.

Details

Language :
English
ISSN :
1678-9849
Volume :
54
Database :
MEDLINE
Journal :
Revista da Sociedade Brasileira de Medicina Tropical
Publication Type :
Academic Journal
Accession number :
33338110
Full Text :
https://doi.org/10.1590/0037-8682-0262-2020