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Long-Term Follow-Up of Percutaneous Coronary Intervention With Paclitaxel-Eluting Balloon Catheter.
- Source :
-
Angiology [Angiology] 2021 Apr; Vol. 72 (4), pp. 364-370. Date of Electronic Publication: 2020 Dec 17. - Publication Year :
- 2021
-
Abstract
- Drug-eluting balloons currently constitute a therapeutic tool used in percutaneous coronary interventions (PCI). Long-term results remain unknown. We evaluated the prognosis of PCI using a second generation paclitaxel-eluting balloon (PEB) in real-world patients. We included all PCI with PEB in de novo or in-stent restenosis coronary lesions performed in our unit from March 2009 to March 2019. We assessed the composite of major adverse cardiovascular events (MACE) rate after a median follow-up of 42 months. Consecutive patients (n = 320) with 386 lesions were included; 46.9% presented with stable angina and 53.1% acute coronary syndromes; 52.6% of the lesions were in-stent restenosis and 47.3% de novo lesions with a mean diameter of 2.4 ± 0.5 mm. A bare metal stent was implanted in 6.7% and a drug-eluting stent in 8.5% of patients. The MACE rate was 8%: 10 (2.6%) cardiovascular deaths, 13 (3.4%) myocardial infarctions, and 16 (4.1%) target lesion revascularization. The all-cause death rate was 5.2%. No cases of thrombosis were recorded. In conclusion, PEB was a safe and effective tool to treat in-stent restenosis and de novo coronary lesions, especially small vessel disease, during long-term follow-up.
- Subjects :
- Acute Coronary Syndrome diagnostic imaging
Acute Coronary Syndrome mortality
Aged
Angioplasty, Balloon, Coronary adverse effects
Angioplasty, Balloon, Coronary mortality
Cardiovascular Agents adverse effects
Coronary Artery Disease diagnostic imaging
Coronary Artery Disease mortality
Coronary Restenosis diagnostic imaging
Coronary Restenosis mortality
Equipment Design
Female
Humans
Male
Middle Aged
Paclitaxel adverse effects
Prospective Studies
Time Factors
Treatment Outcome
Acute Coronary Syndrome therapy
Angioplasty, Balloon, Coronary instrumentation
Cardiac Catheters
Cardiovascular Agents therapeutic use
Coated Materials, Biocompatible
Coronary Artery Disease therapy
Coronary Restenosis therapy
Paclitaxel therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1940-1574
- Volume :
- 72
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Angiology
- Publication Type :
- Academic Journal
- Accession number :
- 33334115
- Full Text :
- https://doi.org/10.1177/0003319720979246